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Occupational contact allergy: The European perspective-Analysis of patch test data from ESSCA between 2011 and 2020

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dc.contributor.author Bauer, Andrea
dc.contributor.author Giménez Arnau, Anna Maria
dc.contributor.author Uter, Wolfgang
dc.date.accessioned 2024-04-17T06:20:30Z
dc.date.available 2024-04-17T06:20:30Z
dc.date.issued 2023
dc.identifier.citation Bauer A, Pesonen M, Brans R, Caroppo F, Dickel H, Dugonik A, et al. Occupational contact allergy: The European perspective-Analysis of patch test data from ESSCA between 2011 and 2020. Contact Dermatitis. 2023 Apr;88(4):263-74. DOI: 10.1111/cod.14280
dc.identifier.issn 0105-1873
dc.identifier.uri http://hdl.handle.net/10230/59801
dc.description.abstract Background Occupational skin diseases have led the occupational disease statistics in Europe for many years. Especially occupational allergic contact dermatitis is associated with a poor prognosis and low healing rates leading to an enormous burden for the affected individual and for society. Objectives To present the sensitization frequencies to the most relevant allergens of the European baseline series in patients with occupational contact dermatitis (OCD) and to compare sensitization profiles of different occupations. Methods The data of 16 022 patients considered having OCD after patch testing within the European Surveillance System on Contact Allergies (ESSCA) network between January 2011 and December 2020 were evaluated. Patients (n = 46 652) in whom an occupational causation was refuted served as comparison group. Results The highest percentages of OCD were found among patients working in agriculture, fishery and related workers, metal industry, chemical industry, followed by building and construction industry, health care, food and service industry. Sensitizations to rubber chemicals (thiurams, carbamates, benzothiazoles) and epoxy resins were associated with at least a doubled risk of OCD. After a decline from 2014 onwards, the risks to acquire an occupation-related sensitization to methyl(chloro)isothiazolinone (MCI/MI) and especially to methylisothiazolinone (MI) seem to increase again. Sensitization rates to formaldehyde were stable, and to methyldibromo glutaronitrile (MDBGN) slightly decreasing over time. Conclusions Among allergens in the European Baseline Series, occupational relevance is most frequently attributed to rubber accelerators, epoxy resins and preservatives.
dc.format.mimetype application/pdf
dc.language.iso eng
dc.publisher Wiley
dc.relation.ispartof Contact Dermatitis. 2023 Apr;88(4):263-74
dc.rights © 2023 The Authors. Contact Dermatitis published by John Wiley & Sons Ltd. This is an open access article under the terms of the Creative Commons Attribution (CC BY) License (http://creativecommons.org/licenses/by/4.0/), which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
dc.rights.uri http://creativecommons.org/licenses/by/4.0/
dc.title Occupational contact allergy: The European perspective-Analysis of patch test data from ESSCA between 2011 and 2020
dc.type info:eu-repo/semantics/article
dc.identifier.doi http://dx.doi.org/10.1111/cod.14280
dc.subject.keyword Baseline series
dc.subject.keyword Clinical epidemiology
dc.subject.keyword Occupational contact allergy
dc.subject.keyword Patch testing
dc.subject.keyword RRID:SCR_001905
dc.subject.keyword Surveillance
dc.rights.accessRights info:eu-repo/semantics/openAccess
dc.type.version info:eu-repo/semantics/publishedVersion


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