Browsing by Author "Roignant, Jean-Yves"

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  • Comprehensive map of ribosomal 2'-O-methylation and C/D box snoRNAs in Drosophila melanogaster
    Sklias, Athena; Cruciani, Sonia; Marchand, Virginie; Spagnuolo, Mariangela; Lavergne, Guillaume; Bourguignon, Valérie; Brambilla, Alessandro; Dreos, René; Marygold, Steven J.; Novoa Pardo, Ana María, 1979-; Motorin, Yuri; Roignant, Jean-Yves (Oxford University Press, 2024)
    During their maturation, ribosomal RNAs (rRNAs) are decorated by hundreds of chemical modifications that participate in proper folding of rRNA secondary structures and therefore in ribosomal function. Along with pseudouridine, ...
  • Enhanced detection of RNA modifications and read mapping with high-accuracy nanopore RNA basecalling models
    Diensthuber, Gregor; Pryszcz, Leszek Piotr, 1985-; Llovera Nadal, Laia; Lucas, Morghan C.; Delgado-Tejedor, Anna; Cruciani, Sonia; Roignant, Jean-Yves; Begik, Oguzhan; Novoa, Eva Maria (Cold Spring Harbor Laboratory Press (CSHL Press), 2024)
    In recent years, nanopore direct RNA sequencing (DRS) became a valuable tool for studying the epitranscriptome, due to its ability to detect multiple modifications within the same full-length native RNA molecules. While ...
  • Parallel evolution of a splicing program controlling neuronal excitability in flies and mammals
    Torres Méndez, Antonio, 1992-; Pop, Sinziana; Bonnal, Sophie; Almudi, Isabel; Avola, Alida; Roberts, Ruairí J. V.; Paolantoni, Chiara; Alcaina-Caro, Ana; Martín-Anduaga, Ane; Haussmann, Irmgard U.; Morin, Violeta; Casares, Fernando; Soller, Matthias; Kadener, Sebastian; Roignant, Jean-Yves; Prieto-Godino, Lucia; Irimia Martínez, Manuel (American Association for the Advancement of Science (AAAS), 2022)
    Alternative splicing increases neuronal transcriptomic complexity throughout animal phylogeny. To delve into the mechanisms controlling the assembly and evolution of this regulatory layer, we characterized the neuronal ...

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