Browsing by Author "Cruciani, Sonia"

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  • Comprehensive map of ribosomal 2'-O-methylation and C/D box snoRNAs in Drosophila melanogaster
    Sklias, Athena; Cruciani, Sonia; Marchand, Virginie; Spagnuolo, Mariangela; Lavergne, Guillaume; Bourguignon, Valérie; Brambilla, Alessandro; Dreos, René; Marygold, Steven J.; Novoa Pardo, Ana María, 1979-; Motorin, Yuri; Roignant, Jean-Yves (Oxford University Press, 2024)
    During their maturation, ribosomal RNAs (rRNAs) are decorated by hundreds of chemical modifications that participate in proper folding of rRNA secondary structures and therefore in ribosomal function. Along with pseudouridine, ...
  • Enhanced detection of RNA modifications and read mapping with high-accuracy nanopore RNA basecalling models
    Diensthuber, Gregor; Pryszcz, Leszek Piotr, 1985-; Llovera Nadal, Laia; Lucas, Morghan C.; Delgado-Tejedor, Anna; Cruciani, Sonia; Roignant, Jean-Yves; Begik, Oguzhan; Novoa, Eva Maria (Cold Spring Harbor Laboratory Press (CSHL Press), 2024)
    In recent years, nanopore direct RNA sequencing (DRS) became a valuable tool for studying the epitranscriptome, due to its ability to detect multiple modifications within the same full-length native RNA molecules. While ...
  • Quantitative profiling of pseudouridylation dynamics in native RNAs with nanopore sequencing
    Begik, Oguzhan; Lucas, Morghan C.; Pryszcz, Leszek Piotr, 1985-; Ramirez, Jose Miguel; Medina, Rebeca; Milenkovic, Ivan; Cruciani, Sonia; Liu, Huanle; Santos Vieira, Helaine Graziele; Sas Chen, Aldema; Mattick, John S.; Schwartz, Schraga; Novoa, Eva Maria (Nature Research, 2021)
    Nanopore RNA sequencing shows promise as a method for discriminating and identifying different RNA modifications in native RNA. Expanding on the ability of nanopore sequencing to detect N6-methyladenosine, we show that ...
  • Subcellular relocalization and nuclear redistribution of the RNA methyltransferases TRMT1 and TRMT1L upon neuronal activation
    Jonkhout, Nicky; Cruciani, Sonia; Santos Vieira, Helaine Graziele; Tran, Julian; Liu, Huanle; Liu, Ganqiang; Pickford, Russell; Kaczorowski, Dominic; Franco, Gloria R.; Vauti, Franz; Camacho, Noelia; Abedini, Seyedeh Sedigheh; Najmabadi, Hossein; Ribas de Pouplana, Lluís; Christ, Daniel; Schonrock, Nicole; Mattick, John S.; Novoa, Eva Maria (Taylor & Francis, 2021)
    RNA modifications are dynamic chemical entities that expand the RNA lexicon and regulate RNA fate. The most abundant modification present in mRNAs, N6-methyladenosine (m6A), has been implicated in neurogenesis and memory ...

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