Browsing by Author "Carolis, Carlo"

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  • SARS-CoV-2 infection, vaccination, and antibody response trajectories in adults: a cohort study in Catalonia
    Karachaliou, Marianna; Moncunill, Gemma; Espinosa Díaz, Ana; Castaño Vinyals, Gemma; Rubio, Rocío; Vidal, Marta; Jiménez, Alfons; Prados, Esther; Bañuls, Marc; Melero, Natalia Rodrigo; Izquierdo, Luis; Carolis, Carlo; Goldberg, Ximena; Aguilar, Ruth; García Aymerich, Judith; Kogevinas, Manolis; Dobaño, Carlota (BioMed Central, 2022)
    Background: Heterogeneity of the population in relation to infection, COVID-19 vaccination, and host characteristics is likely reflected in the underlying SARS-CoV-2 antibody responses. Methods: We measured IgM, IgA, and ...
  • SARS-CoV-2 sculpts the immune system to induce sustained virus-specific naïve-like and memory B-cell responses
    Campos Mata, Leire de, 1991-; Tejedor Vaquero, Sonia, 1988-; Tachó-Piñot, Roser; Piñero González, Janet, 1977-; Grasset, Emilie K.; Arrieta Aldea, Itziar; Rodrigo Melero, Natalia; Carolis, Carlo; Horcajada Gallego, Juan Pablo; Cerutti, Andrea, 1965-; Villar García, Judit; Magri, Giuliana, 1978- (Wiley Open Access, 2021)
    Objectives: SARS-CoV-2 infection induces virus-reactive memory B cells expressing unmutated antibodies, which hints at their emergence from naïve B cells. Yet, the dynamics of virus-specific naïve B cells and their impact ...
  • SARS-CoV-2 seroprevalence study in pediatric patients and health care workers using multiplex antibody immunoassays
    Prados de la Torre, Esther; Obando, Ignacio; Vidal, Marta; Felipe, Beatriz de; Aguilar, Ruth; Izquierdo, Luis; Carolis, Carlo; Olbrich, Peter; Capilla-Miranda, Ana; Serra, Pau; Santamaria, Pere; Blanco-Lobo, Pilar; Moncunill, Gemma; Rodríguez-Ortega, Manuel J.; Dobaño, Carlota (MDPI, 2022)
    SARS-CoV-2 infection has become a global health problem specially exacerbated with the continuous appearance of new variants. Healthcare workers (HCW) have been one of the most affected sectors. Children have also been ...
  • Seroprevalence and socioeconomic impact of the first SARS-CoV-2 infection wave in a small town in Navarre, Spain
    Ribes, Marta; Montañà, Júlia; Vidal, Marta; Aguilar, Ruth; Nicolás, Patricia; Alfonso, Uxue; Rodrigo Melero, Natalia; Carolis, Carlo; Dobaño, Carlota; Moncunill, Gemma; Chaccour, Carlos (Nature Research, 2023)
    The characterization of the antibody response to SARS-CoV-2 and its determinants are key for the understanding of COVID-19. The identification of vulnerable populations to the infection and to its socioeconomic impact is ...
  • Seroprevalence of antibodies against SARS-CoV-2 among health care workers in a large Spanish reference hospital
    Garcia Basteiro, Alberto L.; Carolis, Carlo; Hecht, Jochen; Dobaño, Carlota (Nature Research, 2020)
    Health care workers (HCW) are a high-risk population to acquire SARS-CoV-2 infection from patients or other fellow HCW. This study aims at estimating the seroprevalence against SARS-CoV-2 in a random sample of HCW from a ...
  • Seven-month kinetics of SARS-CoV-2 antibodies and role of pre-existing antibodies to human coronaviruses
    Ortega, Natalia; Ribes, Marta; Vidal, Marta; Rubio, Rocío; Aguilar, Ruth; Williams, Sarah; Barrios, Diana; Alonso, Selena; Mitchell, Robert A.; Jairoce, Chenjerai; Cruz, Angeline; Jimenez, Alfons; Santano, Rebeca; Méndez, Susana; Lamoglia, Montserrat; Rosell, Neus; Llupià, Anna; Puyol, Laura; Chi, Jordi; Rodrigo Melero, Natalia; Mayor, Alfredo; Vilella, Anna; Trilla, Antoni; Carolis, Carlo; Izquierdo, Luis; García-Basteiro, Alberto L.; Moncunill, Gemma; Dobaño, Carlota (Nature Research, 2021)
    Unraveling the long-term kinetics of antibodies to SARS-CoV-2 and the individual characteristics influencing it, including the impact of pre-existing antibodies to human coronaviruses causing common cold (HCoVs), is essential ...
  • Sustained seropositivity up to 20.5 months after COVID-19
    Dobaño, Carlota; Ramírez-Morros, Anna; Alonso, Selena; Rubio, Rocío; Ruiz-Olalla, Gemma; Vidal Alaball, Josep; Macià, Dídac; Miró Catalina, Queralt; Vidal, Marta; Fuster Casanovas, Aina; Prados de la Torre, Esther; Barrios, Diana; Jiménez, Alfons; Zanoncello, Jasmina; Rodrigo Melero, Natalia; Carolis, Carlo; Izquierdo, Luis; Aguilar, Ruth; Moncunill, Gemma; Ruiz-Comellas, Anna (BioMed Central, 2022)
    This study evaluated the persistence of IgM, IgA, and IgG to SARS-CoV-2 spike and nucleocapsid antigens up to 616 days since the onset of symptoms in a longitudinal cohort of 247 primary health care workers from Barcelona, ...
  • TANGO1 inhibitors reduce collagen secretion and limit tissue scarring
    Raote, Ishier; Häkkinen, Hanna-Maria; Vibe, Carine; Broadbent, Katrina; Carolis, Carlo; Ruprecht, Verena; Malhotra, Vivek (Nature Research, 2024)
    Uncontrolled secretion of ECM proteins, such as collagen, can lead to excessive scarring and fibrosis and compromise tissue function. Despite the widespread occurrence of fibrotic diseases and scarring, effective therapies ...
  • The mRNA-1273 vaccine induces cross-variant antibody responses to SARS-CoV-2 with distinct profiles in individuals with or without pre-existing immunity
    Tejedor Vaquero, Sonia, 1988-; Campos Mata, Leire de, 1991-; Ramada Rodilla, José María, 1961-; Díaz, Pilar; Navarro-Barriuso, Juan; Ribas-Llauradó, Clara; Rodrigo Melero, Natalia; Carolis, Carlo; Cerutti, Andrea, 1965-; Gimeno Martínez, Ramón; Magri, Giuliana, 1978- (Frontiers Media, 2021)
    mRNA-based vaccines effectively induce protective neutralizing antibodies against SARS-CoV-2, the etiological agent of COVID-19. Yet, the kinetics and compositional patterns of vaccine-induced antibody responses to the ...

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